Mechanisms of disease: hepatic steatosis in type 2 diabetes—pathogenesis and clinical relevance
M Roden - Nature clinical practice Endocrinology & metabolism, 2006 - nature.com
… in the formation of liver glycogen, as … liver is termed hepatic steatosis. Absence of both
significant alcohol consumption and other liver disease is the criterion for defining simple hepatic …
significant alcohol consumption and other liver disease is the criterion for defining simple hepatic …
[HTML][HTML] Nonalcoholic fatty liver disease and type 2 diabetes: Pathophysiological mechanisms shared between the two faces of the same coin
C Acierno, A Caturano, PC Pafundi… - Exploration of …, 2020 - explorationpub.com
… hepatic steatosis is a phenotype that recognizes diverse and complex causes and a wide
spectrum of clinical … or without T2DM, supports the clinical relevance of such a mechanism [51]. …
spectrum of clinical … or without T2DM, supports the clinical relevance of such a mechanism [51]. …
Metabolic liver disease in diabetes–from mechanisms to clinical trials
… mechanisms underlying T2DM and NAFLD, the relevance of … of subgroups at specific risk
of disease progression. Also, the … , liver steatosis could be associated with hepatic insulin …
of disease progression. Also, the … , liver steatosis could be associated with hepatic insulin …
[HTML][HTML] Non-alcoholic fatty liver disease (NAFLD), type 2 diabetes, and non-viral hepatocarcinoma: Pathophysiological mechanisms and new therapeutic strategies
E Vetrano, L Rinaldi, A Mormone, C Giorgione… - Biomedicines, 2023 - mdpi.com
… hepatic steatosis progression through several mechanisms, … apoptosis, in a fatty liver than
in a healthy liver. In addition, a … importance of Tregs in NAFLD and NASH, providing clinical …
in a healthy liver. In addition, a … importance of Tregs in NAFLD and NASH, providing clinical …
Understanding the mechanisms of reversal of type 2 diabetes
… summarise the studies relevant to the understanding of type 2 diabetes as a reversible clinical
state. … Because hepatic steatosis is now the most common cause of moderately raised ALT …
state. … Because hepatic steatosis is now the most common cause of moderately raised ALT …
Effects of pioglitazone on serum fetuin-A levels in patients with type 2 diabetes mellitus
K Mori, M Emoto, T Araki, H Yokoyama, E Lee… - Metabolism, 2008 - Elsevier
… type 2 diabetes mellitus and related atherosclerotic diseases. Although the precise mechanism
… both treating diabetes and preventing cardiovascular diseases. For this purpose, insulin-…
… both treating diabetes and preventing cardiovascular diseases. For this purpose, insulin-…
Pharmacological management of nonalcoholic fatty liver disease in type 2 diabetes
… (NASH) and drugs under development that target relevant pathogenetic pathways. However,
to date … mechanisms that link hepatic steatosis with insulin resistance and type 2 diabetes. …
to date … mechanisms that link hepatic steatosis with insulin resistance and type 2 diabetes. …
Non-alcoholic fatty liver disease in type 2 diabetes: pathogenesis and treatment options
K Tziomalos, VG Athyros… - Current vascular …, 2012 - ingentaconnect.com
… and T2DM is of paramount importance for the reduction of the … for hepatic steatosis and
non-alcoholic fatty liver disease in … 2E1 in non-alcoholic fatty liver disease: mechanisms and …
non-alcoholic fatty liver disease in … 2E1 in non-alcoholic fatty liver disease: mechanisms and …
Subtypes of type 2 diabetes determined from clinical parameters
… pathways involved in diabetes pathogenesis are represented as … one mechanism would
be identified to study the mechanism in … using these clinically relevant parameters provides a …
be identified to study the mechanism in … using these clinically relevant parameters provides a …
The role of metformin and thiazolidinediones in the regulation of hepatic glucose metabolism and its clinical impact
E Phielix, J Szendroedi, M Roden - Trends in Pharmacological Sciences, 2011 - cell.com
… hyperglycemia and EGP in clinical trials, only TZDs decrease steatosis and peripheral insulin
… cellular mechanisms underlying the effects of metformin, the only biguanide in clinical use, …
… cellular mechanisms underlying the effects of metformin, the only biguanide in clinical use, …